Drug Standards
![Medchemexpress LLC 2-[[4-[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]imino]-1,4-dihydro-1-oxo-2-naphthalenyl]thio]-acetic acid | 881487-77-0 | 98.0% | 443.54 g/mol | C22H21NO5S2 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239369.png-250.jpg)
Medchemexpress LLC 2-[[4-[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]imino]-1,4-dihydro-1-oxo-2-naphthalenyl]thio]-acetic acid | 881487-77-0 | 98.0% | 443.54 g/mol | C22H21NO5S2 | 10MG
KPT-6566 is a selective, covalent inhibitor of the prolyl isomerase PIN1 that binds the enzyme's catalytic site, promotes PIN1 degradation, and induces DNA damage responses and cell death in cancer models. It is supplied as a solid and as DMSO solutions and is intended for biochemical and cell-based research targeting PIN1-dependent pathways.
- Selective, covalent inhibitor of prolyl isomerase PIN1.
- Binds the catalytic site and promotes PIN1 degradation.
- Demonstrated biochemical potency (PIN1 PPIase IC50 ≈ 640 nM; Ki ≈ 625 nM).
- High purity: 98.0%.
- Molecular formula C22H21NO5S2; molecular weight 443.54 g/mol.
- Available as solid (multiple mg sizes) and as 10 mM solutions in DMSO for assays.
- Suitable for biochemical assays and cell-based cancer research.
Selleck Chemical LLC Naproxen Sodium S1626-50mg
Naproxen Sodium (RS-3650) is a COX inhibitor for COX-1 and COX-2 with IC50 of 8 7 M and 5 2 M respectively
Selleck Chemical LLC Triamcinolone Acetonide S1628-50mg
Triamcinolone acetonide is a synthetic glucocorticoid used in the symptomatic treatment of inflammation
Medchemexpress LLC Cabozantinib S-malate | 1140909-48-3 | 99.9% | 200MG
Cabozantinib S-malate | 1140909-48-3 | 99.9% | 200MG
Apexbio Technology LLC Benazepril 86541-75-5 10mg
Benazepril (CAS 86541-75-5) is a small molecule inhibitor of angiotensin-converting enzyme (ACE) a key enzyme responsible for the conversion of angiotensin I to the vasoconstrictor angiotensin II By blocking ACE activity benazepril reduces the synthesis of angiotensin II leading to diminished vasoconstriction and lowered blood pressure In biomedical research benazepril is utilized to investigate the renin-angiotensin system cardiovascular regulation and mechanisms underlying hypertension Its pharmacological profile supports its application in studies focused on cardiovascular diseases and renal function
Apexbio Technology LLC FITC-Dextran (MW 150000) 10mg
FITC-Dextran MW 150000 (CAS 60842-46-8) is a fluorescent polysaccharide probe composed of dextran covalently labeled with fluorescein isothiocyanate (FITC) It is designed as a macromolecular marker to study cell membrane permeability and barrier integrity in biological systems FITC-Dextran MW 150000 functions by emitting detectable green fluorescence after excitation enabling quantitative analysis of transport dynamics and permeability Based on these properties FITC-Dextran MW 150000 is employed in research applications such as permeability assays evaluation of barrier integrity (blood-brain intestinal vascular) intracellular trafficking studies and assessment of fluid-phase uptake processes
Medchemexpress LLC Mogroside VI | 189307-15-1 | 98.5% | 1449.58 | C66H112O34 | 1 MG
Mogroside VI is a triterpenoid glycoside isolated from Siraitia grosvenorii (monk fruit) and used as a non-sugar, high-intensity sweetener for research. It has reported antioxidant, antidiabetic, and anticancer activities and is supplied with supporting COA and SDS documentation for characterization and quality control.
- High-purity research reagent (98.45%).
- Non-sugar, high-intensity sweetener for formulation and bioactivity studies.
- Reported antioxidant, antidiabetic, and anticancer activity.
- Molecular formula C66H112O34; molecular weight 1449.58.
- Supplied with COA and SDS for traceability and quality control.
![eMolecules 19455-23-3 | Potassium pivalate | Synthonix - Stock | MFCD00671345 | 140.223 | C5H9KO2 | 95.000 | [K+].CC(C)(C)C([O-])=O | 100g | 448043525](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000170887.jpg-250.jpg)
eMolecules 19455-23-3 | Potassium pivalate | Synthonix - Stock | MFCD00671345 | 140.223 | C5H9KO2 | 95.000 | [K+].CC(C)(C)C([O-])=O | 100g | 448043525
Potassium pivalate | Synthonix - Stock | 19455-23-3 | MFCD00671345 | 140.223 | C5H9KO2 | 95.000 | [K+].CC(C)(C)C([O-])=O | 100g | 448043525
Medchemexpress LLC Berberine (chloride hydrate) | 68030-18-2 | 99.69% | 389.83 | 1 G
Berberine chloride hydrate is an alkaloid that acts as an antibiotic. It induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. It also possesses antineoplastic properties.
- Acts as an antibiotic.
- Induces reactive oxygen species (ROS) generation.
- Inhibits DNA topoisomerase.
- Has antineoplastic properties.
- Shows potential inhibitory effects on the proliferation of four colorectal carcinoma cell lines in vitro.
- Induces a time- and dose-dependent inhibition of LoVo cell growth.
- Exposure to 40 μM induces G2/M-phase cell cycle arrest in LoVo cells.
- Suppresses cyclin B1, cdc2, and cdc25c protein expression in LoVo cells.
- Inhibits the growth of human colorectal adenocarcinoma in vivo at doses of 30 and 50 mg/kg/day.
Medchemexpress LLC Benzarone | 1477-19-6 | >98% | 266.29 | 100 MG
Benzarone is identified as an oral inhibitor of human urate transporter 1 (hURAT1), possessing an IC50 value of 2.8 μM. It also functions as an uncoupler of oxidative phosphorylation.
- Oral inhibitor of human urate transporter 1 (hURAT1).
- Acts as an uncoupler of oxidative phosphorylation.
- Can be utilized to reduce serum uric acid levels.
- Useful for research in vascular diseases.
Medchemexpress LLC Rosuvastatin sodium | 147098-18-8 | 99.9% | 503.52 | 1 ML
Rosuvastatin Sodium is a potent and selective competitive inhibitor of HMG-CoA reductase (HMGCR) with an IC50 of 11 nM. It also potently blocks hERG current with an IC50 of 195 nM. This compound reduces the expression of mature hERG and its interaction with heat shock protein 70 (Hsp70), contributing to its biological activity. Rosuvastatin Sodium is effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels. It is intended for research use only.
- Competitive HMG-CoA reductase (HMGCR) inhibitor
- Potently blocks hERG current
- Reduces expression of mature hERG protein
- Lowers LDL cholesterol and triglycerides
- Reduces C-reactive protein levels
U.S. Pharmacopeia PYRANTEL RELATED COMPOUND A
Pyrantel Related Compound A (25 mg) (1-methyl-2-[(Z)-2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine Pamoate)
